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Computational modelling of blood flow in the carotid artery with serial stenosis
Lukáš, Petr ; Hájek, Petr (referee) ; Švancara, Pavel (advisor)
The aim of this bachelor's thesis is to analyse the effect of double stenosis on flow and stress characteristics in the carotid artery. First, based on the stated literature, a literature search is conducted regarding blood flow in the arterial system. Then, the procedure of creating idealized models of an artery with double stenosis and the procedure of mesh creation and numerical solution are described. The models have different size of the stenosis and different distance between stenosis. In the final stage, the results are analysed first for stationary flow, then one model is selected on which is performed the analysis for pulsating flow. Analytical calculation of pressure drop and comparison with numerical calculation is also part of this work.
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Methods for flow estimation using laser speckle contrast imaging
Jahůdková, Michaela ; Harabiš, Vratislav (referee) ; Kolář, Radim (advisor)
This thesis deals with introduction to optical method called laser speckle contrast imaging (LSCI). The thesis contains a description of the basic theory that is related to the method, the LSCI own principle, the characteristics of this technique, its applications and also a description of various variants of LSCI. The second part of the thesis deals with the modification of acquisition software to be suitable for measurement of multi-exposure LSCI (MESI), verification of this method by experiment and conclusions of evaluated of data.
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Detector of bubbles in blood
Foltýn, Vojtěch ; Sekora, Jiří (referee) ; Rozman, Jiří (advisor)
ABSTRAKT This thesis is the theoretical part deals with various ways of cleansing the blood, with a focus on hem dialysis. Describes the technical solution and monitor the dialysis flow diagram of blood and dialysate. The paper describes various solutions to detect bubbles in the blood and their advantages and disadvantages. Based on the best method of detection are designed detector bubbles. Working in the practical part contains a proposal detector set for venous diameter of 20 mm. Equipment to detect bubbles allows for connection to a blood pump discontinue its activities. Output works are drawing diagrams, printed circuit board design and implementation of graphs circuits.
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Validaton of multichannel bioimpedance of vessels using synchronized vascular ultrasonography
Hidegová, Simona ; Kolářová, Jana (referee) ; Mézl, Martin (advisor)
The inclusion of a new device in clinical practice requires an adequate validation. The original publication which introduced multichannel bioimpedance monitor MBM was focused on discribing its technical parameters and demonstration measurements. Further evaluation desires comparision with other standard measuring device. This thesis describes pulse wave measurement by MBM and by other medical devices used for establishing cardiovascular risk. It proposes the validation experiment with synchronized vascular ultrasonography as a reference method. The process of the experimental measurement, aquired data and following data analysis are described in detail. The outputs of the experiment are statistically evaluated. The MBM’s performance and design of the experiment are discussed.
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Ultrasound blood flow detector
Kameníček, Robert ; Dlouhý, Jiří (referee) ; Rozman, Jiří (advisor)
My master’s thesis deals with methods of measuring the ultrasonic blood flow blood vessel with a detailed focus on Doppler ultrasound systems, which find application in the diagnosis of superficial vascular and obstetrics. The thesis is described a proposal indicating polydirectional Doppler system with a continuous carrier wave frequency of 4 MHz, the intensity of ultrasound 100 mW/cm2 and diameter D-shaped transducers 8 mm. As a result, the indicator will be able to measure blood flow velocity in the range of 5-40 cm/s, which appears to 3.5 digit display. After describing important theoretical assumptions, the work pays block diagram indicator. Furthermore, it examines the various functional blocks on the requirements imposed on them. It looks at the options of each functional block, and finally describes the implementation of the selected option and including peripheral solutions. Great attention is paid to the power of the indicator, where the power supply will be used 9 V battery. Create a symmetric voltage for operate amplifier and other auxiliary voltage will procure DC/DC converters. In conclusion, the work is located around the perimeter solutions indicator. The following draft for the production of double-sided PCB, its installation and a list of elements. The outcome of the thesis is complete documentation for the implementation of an indicator of blood flow, which allows us to obtain information on throughput vessels, especially the lower and upper limbs.
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Doppler blood flow indicator
Böhm, Richard ; Bubník, Karel (referee) ; Rozman, Jiří (advisor)
This bachelor‘s thesis deals with literature search of basis of ultrasonic and Doppler methods of measuring blood flow velocity. It also deals with the evaluation of Doppler signals and with the individual functional system blocks, with the indicator of blood flow with the operating frequency of 4 MHz, with the generated ultrasonic intensity of 100 mW/cm2 and with the average transmitting changer in shape of D = 8 mm. Furthermore, experimental verification of individual system components is included.
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Modeling and animation of biological structures
Matulík, Martin ; Bílek, Michal (referee) ; Maxa, Jiří (advisor)
Following work deals with subject matter of digital modelling and animation of biological structures. Software tools for computer generated images (CGI), well proven in common practice, are evaluated, as well as tools for specific activities, available inside chosen software environment. Among vast pool of modelling approaches are discussed tools suitable for creation and representation of selected structures, along with tools essential for their consequent animation. Possible rendering approaches and their parameters in relation to qualities of resulting computer-generated images are discussed as well. Above-mentioned approaches will be consequently utilized for modelling, physical simulation and animation of erythrocyte’s flow throughout blood vessel in following project. Resulting output of that work will be based on series of digital images, suitable for creating video-sequence containing abovementioned animation in end-user digestible form.
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Ultrasound blood flow detector
Vožda, Michal ; Dlouhý, Jiří (referee) ; Rozman, Jiří (advisor)
This work deals with Doppler methods of measuring blood flow in blood vessels and a simple design with a continuous wave for the 4 MHz frequency and intensity of ultrasound 100 mW/cm2. The work contains a description of the functional blocks and design of their involvement. Individual blocks are simulated in PSpice. The resulting circuit is a printed circuit board and a 3D model of the plate fitted in EAGLE.
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Ultrasound blood flowmeter for haemodialysis monitor
Krohová, Lucie ; Sekora, Jiří (referee) ; Rozman, Jiří (advisor)
The main objective of this thesis is to get know about introduce the principles of hemodialysis, blood flow measurement methods and the creation the system and peripheral design of blood flow meter. The thesis contains an introduction to hemodialysis, a description of the dialysis monitor, the distribution of ultrasonic flow meters and system design of blood flow meter with a brief description of each function block, circuit diagram of a flow meter and experimental verification of the circuit. There are also the list of components, printed circuit board drawing and technical drawing of the sensor included.
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Acquisition, Modeling and Signal Processing in Ultrasound Perfusion Imaging
Mézl, Martin ; Kozubek, Michal (referee) ; Flusser,, Jan (referee) ; Jiřík, Radovan (advisor)
This work deals with possibilities of ultrasound perfusion analysis for the absolute quantification of perfusion parameters. In the theoretical part of this work are discussed possibilities of using of the ultrasound contrast agents and approaches for the perfusion analysis. New methods for the perfusion analysis are suggested and tested in the practical part of this work. The methods are based on convolutional model in which the concentration of the contrast agent is modeled as aconvolution of the arterial input function and the tissue residual function. The feasibility of these methods for the absolute quantification of perfusion parameters is shown on data from phantom studies, simulations and also preclinical and clinical studies. The software for the whole process of the perfusion analysis was developed for using in hospitals.
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